Screening for high-grade cervical intra-epithelial neoplasia and cancer by testing for high-risk HPV, routine cytology or colposcopy.

@article{Schneider2000ScreeningFH,
  title={Screening for high-grade cervical intra-epithelial neoplasia and cancer by testing for high-risk HPV, routine cytology or colposcopy.},
  author={Antonius Schneider and Heike Hoyer and Bernhard Lotz and S Leistritza and Rosemarie Kuehne-Heid and Ingo Nindl and Beat M{\"u}ller and Johannes Haerting and Matthias D{\"u}rst},
  journal={International journal of cancer},
  year={2000},
  volume={89 6},
  pages={
          529-34
        }
}
The validity of testing for high-risk types of human papillomavirus (HPV) in cervical cancer prevention programs is undetermined. We compared the performance on primary screening of HPV DNA testing, cytology and colposcopy in detecting cervical intra-epithelial neoplasia (CIN) grade 2 or 3 or cancer. A cohort of 4,761 women, median age 35 years, was screened by routine cytology, routine colposcopy and testing for high-risk HPV by a PCR-based method. Within an 8-month period, women with abnormal… CONTINUE READING

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