Screening for hemochromatosis. A public health perspective.

  title={Screening for hemochromatosis. A public health perspective.},
  author={Mary E Cogswell and Wylie Burke and Sharon M McDonnell and Adele L Franks},
  journal={American journal of preventive medicine},
  volume={16 2},
CONTEXT The discovery of the HFE gene in 1996 has introduced DNA testing as a possible tool for screening and diagnosis of hemochromatosis and increased interest in the disorder. Population screening using transferrin saturation has been advocated by experts to permit early detection and treatment with phlebotomy before the onset of clinical disease. METHODS Based on a literature review, we consider the relative risks and merits of two screening tests as part of a broader look at the evidence… CONTINUE READING

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