Screening for hemochromatosis in children of homozygotes: prevalence and cost-effectiveness.

@article{Adams1995ScreeningFH,
  title={Screening for hemochromatosis in children of homozygotes: prevalence and cost-effectiveness.},
  author={Paul C. Adams and Ann E Kertesz and Leslie S Valberg},
  journal={Hepatology},
  year={1995},
  volume={22 6},
  pages={1720-7}
}
Although hereditary hemochromatosis is an autosomal recessive disease, most homozygotes are concerned with the genetic implications for their children. The optimal age for testing children and the cost implications of screening their children have not been clearly established. A clinical database consisting of 255 children from families with at least one homozygote is used to assess the prevalence of homozygotes among children of homozygous parents and to review the biochemical abnormalities… CONTINUE READING