Screening for gene function in chicken embryo using RNAi and electroporation

  title={Screening for gene function in chicken embryo using RNAi and electroporation},
  author={Vladimir Pekarik and Dimitris Bourikas and Nicola Miglino and Pascal Joset and Stephan Preiswerk and Esther T Stoeckli},
  journal={Nature Biotechnology},
In the postgenomic era the elucidation of the physiological function of genes has become the rate-limiting step in the quest to understand the development and function of living organisms. Gene functions cannot be determined by high-throughput methods but require analysis in the context of the entire organism. This is particularly true in the developing vertebrate nervous system. Because of its easy accessibility in the egg, the chicken embryo has been the model of choice for developmental in… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 89 extracted citations

The chicken as a model for embryonic development.

Cytogenetic and genome research • 2007
View 5 Excerpts
Highly Influenced

In vivo comparative study of RNAi methodologies by in ovo electroporation in the chick embryo.

Developmental dynamics : an official publication of the American Association of Anatomists • 2004
View 3 Excerpts
Highly Influenced

K+ Channel Kv3.4 Is Essential for Axon Growth by Limiting the Influx of Ca2+ into Growth Cones.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2017
View 2 Excerpts


Publications referenced by this paper.
Showing 1-10 of 21 references

Similar Papers

Loading similar papers…