Screening for celiac disease in children with type 1 diabetes: two views of the controversy.

@article{Freemark2003ScreeningFC,
  title={Screening for celiac disease in children with type 1 diabetes: two views of the controversy.},
  author={Michael S. Freemark and Lynne L. Levitsky},
  journal={Diabetes care},
  year={2003},
  volume={26 6},
  pages={1932-9}
}
C eliac sprue is a chronic intestinal disorder caused by hypersensitivity to prolamins, the glutamineand proline-rich gluten proteins contained in wheat, rye, and barley. Genetically predisposed subjects who ingest cereal proteins develop an inflammatory enteropathy characterized by proliferation of intraepithelial lymphocytes, crypt hyperplasia, and partial or complete atrophy of small intestinal villi. The inflammatory response is induced by cross-linking and transamidation of gluten peptides… CONTINUE READING