Screening for basic drugs in hair of drug addicts by liquid chromatography/time-of-flight mass spectrometry.

@article{Pelander2008ScreeningFB,
  title={Screening for basic drugs in hair of drug addicts by liquid chromatography/time-of-flight mass spectrometry.},
  author={Anna Pelander and Johanna Ristimaa and Ilpo Juhani Rasanen and Erkki Vuori and Ilkka Ojanper{\"a}},
  journal={Therapeutic drug monitoring},
  year={2008},
  volume={30 6},
  pages={717-24}
}
Hair analysis in forensic and clinical toxicology has been strongly focused on drugs of abuse, and comprehensive, drug class-independent screening methods based on mass spectrometric detection have not been applied to date. In this study, a qualitative drug screening method by liquid chromatography coupled to time-of-flight mass spectrometry, earlier developed and evaluated for forensic toxicological urine analysis, was adapted for screening of basic drugs in hair. The method included alkaline… CONTINUE READING

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