Screening for anti-inflammatory activity of 12 Arnica (Asteraceae) species assessed by inhibition of NF-kappaB and release of human neutrophil elastase.

@article{Ekens2008ScreeningFA,
  title={Screening for anti-inflammatory activity of 12 Arnica (Asteraceae) species assessed by inhibition of NF-kappaB and release of human neutrophil elastase.},
  author={C. Eken{\"a}s and A. Żebrowska and B. Schuler and T. Vrede and K. Andreasen and A. Backlund and I. Merfort and L. Bohlin},
  journal={Planta medica},
  year={2008},
  volume={74 15},
  pages={
          1789-94
        }
}
  • C. Ekenäs, A. Żebrowska, +5 authors L. Bohlin
  • Published 2008
  • Biology, Medicine
  • Planta medica
  • Several species in the genus Arnica have been used in traditional medicine to treat inflammatory-related disorders. Extracts of twelve Arnica species and two species closely related to arnica ( Layia hieracioides and Madia sativa) were investigated for inhibition of human neutrophil elastase release and inhibition of transcription factor NF-kappaB. Statistical analyses reveal significant differences in inhibitory capacities between extracts. Sesquiterpene lactones of the helenanolide type, of… CONTINUE READING
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