Screening for Pancreatic Adenocarcinoma in BRCA2 Mutation Carriers: Results of a Disease Simulation Model.

@article{Pandharipande2015ScreeningFP,
  title={Screening for Pancreatic Adenocarcinoma in BRCA2 Mutation Carriers: Results of a Disease Simulation Model.},
  author={Pari Vijay Pandharipande and Alvin Jeon and Curtis R Heberle and Emily C. Dowling and Chung Yin Kong and Daniel C. Chung and William Robert Brugge and Chin Hur},
  journal={EBioMedicine},
  year={2015},
  volume={2 12},
  pages={1980-6}
}
BACKGROUND BRCA2 mutation carriers are at increased risk for multiple cancers including pancreatic adenocarcinoma (PAC). Our goal was to compare the effectiveness of different PAC screening strategies in BRCA2 mutation carriers, from the standpoint of life expectancy. METHODS A previously published Markov model of PAC was updated and extended to… CONTINUE READING