Screening for Hepatitis C Virus Infection in Adults: U.S. Preventive Services Task Force Recommendation Statement

@article{Moyer2013ScreeningFH,
  title={Screening for Hepatitis C Virus Infection in Adults: U.S. Preventive Services Task Force Recommendation Statement},
  author={Virginia A. Moyer},
  journal={Annals of Internal Medicine},
  year={2013},
  volume={159},
  pages={349 - 357}
}
  • V. Moyer
  • Published 3 September 2013
  • Medicine
  • Annals of Internal Medicine
DESCRIPTION Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for and treatment of hepatitis C virus (HCV) infection in asymptomatic adults. METHODS The Agency for Healthcare Research and Quality commissioned 2 systematic reviews on screening for and treatment of HCV infection in asymptomatic adults, focusing on evidence gaps identified in the previous USPSTF recommendation and new studies published since 2004. The evidence on screening for HCV in… 
Screening for Hepatitis C Virus Infection in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement.
TLDR
It is concluded with moderate certainty that screening for HCV infection in adults aged 18 to 79 years has substantial net benefit and is recommended for all asymptomatic adults without known liver disease.
Universal Screening for Hepatitis C Virus Infection: A Step Toward Elimination.
TLDR
In this issue of JAMA, the US Preventive Services Task Force (USPSTF) has issued new recommendations for hepatitis C virus (HCV) infection screening in the asymptomatic US population, and now recommends screening for HCV infection in adults aged 18 to 79 years regardless of known risk factors.
Updated Hepatitis C Virus Screening Recommendation-A Step Forward.
TLDR
The updated USPSTF HCV screening recommendation aligns with joint American Association for the Study of Liver Diseases–Infectious Diseases Society of America recommendations for one-time HCV testing in all adults 18 years or older and concludes with moderate certainty that implementing such screening will have substantial net benefit.
CDC Recommendations for Hepatitis C Screening Among Adults — United States, 2020
TLDR
CDC is augmenting previous guidance with two new recommendations: 1) hepatitis C screening at least once in a lifetime for all adults aged ≥18 years, except in settings where the prevalence of HCV infection is <0.1% and 2) Hepatitis C screening for all pregnant women during each pregnancy.
Screening for Hepatitis C Virus Infection in Adolescents and Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
TLDR
Direct evidence on the effects of HCV screening on clinical outcomes remains unavailable, but DAA regimens were associated with SVR rates greater than 5% and few short-term harms relative to older antiviral therapies.
Hepatitis C Virus in the US Military Retiree Population: To Screen, or Not to Screen?
TLDR
The military retiree population did not have a lower prevalence of the HCV antibody than the American populace whether screened based on age or traditional RFs, and the CDC guidelines are applicable in this population.
Trends in Liver Transplantation in Hepatitis C Virus–Infected Persons, United States
TLDR
Trends in liver transplantation (LT) waitlist registrations and LT surgeries during 1995–2012 suggest that persons born during 1945–1965 are a distinct birth cohort that is increasingly affected by HCV-related ESLD.
Impact and costs of a hepatitis C virus screening programme for adults hospitalised at an academic medical centre
TLDR
Screening hospitalised patients born between 1945 and 1965 who were seen by the ID Consultation Service would increase screening rates, identify undiagnosed HCV infections and link patients to care.
Chronic hepatitis B and C infection in the United States: a review of current guidelines, disease burden and cost effectiveness of screening
TLDR
This review examines the change in the guidelines, the likely true seroprevalence of hepatitis B and C virus, as well as the burden of chronic infection in this population.
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Screening for Hepatitis C Virus Infection in Adults: Recommendation Statement
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The USPSTF found no evidence that screening for HCV infection in adults at high risk leads to improved long-term health outcomes, although the yield of screening would be substantially higher in a high-risk population than in an average- risk population and there is good evidence that antiviral therapy improves intermediate outcomes, such as viremia.
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