Screening for HIV: Systematic Review to Update the 2005 U.S. Preventive Services Task Force Recommendation

@article{Chou2012ScreeningFH,
  title={Screening for HIV: Systematic Review to Update the 2005 U.S. Preventive Services Task Force Recommendation},
  author={Roger Chou and Shelley Selph and Tracy L Dana and Christina Bougatsos and Bernadette Zakher and Ian Blazina and P. Todd Korthuis},
  journal={Annals of Internal Medicine},
  year={2012},
  volume={157},
  pages={706 - 718}
}
BACKGROUND A 2005 U.S. Preventive Services Task Force (USPSTF) review found good evidence that HIV screening is accurate and that antiretroviral therapy (ART) for immunologically advanced disease is associated with substantial clinical benefits, but insufficient evidence to determine the effects on transmission or in less immunologically advanced disease. PURPOSE To update the 2005 USPSTF review on benefits and harms of HIV screening in adolescents and adults, focusing on research gaps… 
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References

SHOWING 1-10 OF 192 REFERENCES
Screening for HIV: Recommendation Statement
TLDR
The USPSTF found good evidence that both standard and FDA-approved rapid screening tests accurately detect HIV infection in pregnant women and fair evidence that introduction of universal prenatal counseling and voluntary testing increases the proportion of HIV-infected women who receive a diagnosis and are treated before delivery.
Costs and Consequences of the US Centers for Disease Control and Prevention's Recommendations for Opt-Out HIV Testing
TLDR
It is found that for the same programmatic cost of US$864,207,288, targeted counseling and testing services (at a 1% HIV seropositivity rate) would be preferred to opt-out testing: targeted services would newly diagnose more HIV infections, prevent more infections, and do so at a lower gross cost per infection averted.
The Cost-Effectiveness and Population Outcomes of Expanded HIV Screening and Antiretroviral Treatment in the United States
TLDR
Expanding HIV screening and treatment simultaneously offers the greatest health benefit and is cost-effective, however, even substantial expansion of HIV screenings and treatment programs is not sufficient to markedly reduce the U.S. HIV epidemic without substantial reductions in risk behavior.
Expanded screening for HIV in the United States--an analysis of cost-effectiveness.
TLDR
In all but the lowest-risk populations, routine, voluntary screening for HIV once every three to five years is justified on both clinical and cost-effectiveness grounds.
Expanded HIV Screening in the United States: Effect on Clinical Outcomes, HIV Transmission, and Costs
TLDR
A decision model was used to estimate the cost-effectiveness of same-day rapid test HIV screening, considering outcomes experienced by the infected person and his or her sexual contacts, and transmission-related effects.
Cost-Effectiveness of Strategies to Improve HIV Testing and Receipt of Results: Economic Analysis of a Randomized Controlled Trial
TLDR
In a primary-care population, nurse-initiated routine screening with rapid HIV testing and streamlined counseling increased rates of testing and receipt of test results and was cost-effective compared with traditional HIV testing strategies.
Current methods of the US Preventive Services Task Force: a review of the process.
Routine Rapid HIV Screening in Six Community Health Centers Serving Populations at Risk
TLDR
By integrating CDC-recommended guidelines and applying rapid test technology, health centers were able to provide new access to HIV testing andVariation across centers in offering and receiving tests may indicate that clinical training could enhance universal access.
Screening for Human Immunodeficiency Virus in Pregnant Women
TLDR
The SERs and Evidence Syntheses—comprehensive reviews of the scientific evidence on the effectiveness of particular clinical preventive services—serve as the foundation for the recommendations of the USPSTF, which provide age-and risk-factor-specific recommendations for the delivery of these services in the primary care setting.
Screening for HIV in health care settings: a guidance statement from the American College of Physicians and HIV Medicine Association.
TLDR
This guidance statement recommends that clinicians adopt routine screening for HIV and encourage patients to be tested and advises that clinicians determine the need for repeat screening on an individual basis.
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