Screening and characterization of astaxanthin-hyperproducing mutants of Haematococcus pluvialis


Haematococcus pluvialis was mutated by UV or ethyl methanesulphonate. Mutants resistant to nicotine, diphenylamine, fluridone or norflurazon were then selected. Several nicotine-resistant mutants showed increased (1.9% to 2.5% vs. 1.2% w/w) astaxanthin production. Mutants maintained high astaxanthin production over 4 months of repeated culture. 
DOI: 10.1023/A:1022877703008


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