Screening HDAC Inhibitors - A Workflow Comprising High Throughput and High Content Screening

  • Published 2013


An epigenetic trait is a stably inherited phenotype resulting from changes in a chromosome without alterations in the DNA sequence [Berger et al., 2009]. Key mechanisms of epigenetic gene regulation are pathways which affect the packaging of DNA into chromatin, thereby determining the accessibility of DNA to transcription. These pathways include DNA… (More)


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