Screen-detected breast cancers have a lower mitotic activity index

@article{Groenendijk2000ScreendetectedBC,
  title={Screen-detected breast cancers have a lower mitotic activity index},
  author={Richard P. R. Groenendijk and Peter Bult and L Tewarie and Petronella G. M. Peer and Rigtje F. van der Sluis and Theo Ruers and Theo Wobbes},
  journal={British Journal of Cancer},
  year={2000},
  volume={82},
  pages={381 - 384}
}
We know that screening for breast cancer leads to detection of smaller tumours with less lymph node metastases. Could it be possible that the decrease in mortality after screening is not only caused by this earlier stage, but also by a different mitotic activity index (MAI) of the tumours that are detected by screening? Is MAI a prognostic factor for recurrence-free survival? A retrospective study was carried out of 387 patients with breast cancer, treated at the University Hospital Nijmegen… CONTINUE READING

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