Score tests for epistasis models on quantitative traits using general pedigree data.

@article{Wang2003ScoreTF,
  title={Score tests for epistasis models on quantitative traits using general pedigree data.},
  author={Kai Wang},
  journal={Genetic epidemiology},
  year={2003},
  volume={25 4},
  pages={
          314-26
        }
}
  • Kai Wang
  • Published 2003 in Genetic epidemiology
Efficient score tests for a two-locus model for quantitative traits are proposed for general pedigrees. Two search strategies, simultaneous search and conditional search, are considered. These tests are attractive alternatives to the likelihood ratio test for their asymptotic equivalency to their respective likelihood ratio tests and efficiency in computation. The finite-sample properties of these tests are investigated through simulations. Extensions to more complicated models and to other… CONTINUE READING