Scopolamine in rats impairs acquisition but not retention in a 14-unit T-maze.

@article{Spangler1988ScopolamineIR,
  title={Scopolamine in rats impairs acquisition but not retention in a 14-unit T-maze.},
  author={Edward L. Spangler and Mark E. Chachich and Donald K. Ingram},
  journal={Pharmacology, biochemistry, and behavior},
  year={1988},
  volume={30 4},
  pages={949-55}
}
To follow up a previous report noting that scopolamine impaired acquisition performance of young rats in a shock-motivated 14-unit T-maze, the present study assessed the effects of muscarinic antagonism on retention aspects of the same task. The broader objective was to further the investigation of possible defects in cholinergic neurotransmission that might underlie the age-related impairments previously observed in this task. Young (3-month) male F-344 rats were given preliminary training to… CONTINUE READING

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