Scopolamine effects on memory, language, visuospatial praxis and psychomotor speed
@article{Flicker2005ScopolamineEO, title={Scopolamine effects on memory, language, visuospatial praxis and psychomotor speed}, author={C. Flicker and M. Serby and Steven H. Ferris}, journal={Psychopharmacology}, year={2005}, volume={100}, pages={243-250} }
Scopolamine hydrobromide was administered by subcutaneous injection to 30 young subjects in a dose of 0.22 mg/70 kg, 0.43 mg/70 kg, or 0.65 mg/70 kg. Treatment effects were compared to placebo on an extensive cognitive assessment battery. Almost all tests in the battery had been previously administered to Alzheimer's disease patients and nondemented elderly subjects. Scopolamine produced deficits on tests of verbal recall, visuospatial recall, visual recognition memory, visuospatial praxis… CONTINUE READING
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References
SHOWING 1-10 OF 47 REFERENCES
Patterns of memory failure after scopolamine treatment: implications for cholinergic hypotheses of dementia.
- Psychology, Medicine
- Behavioral and neural biology
- 1986
- 238
Psychomotor, physiological and cognitive effects of scopolamine and ephedrine in healthy man
- Medicine
- European Journal of Clinical Pharmacology
- 2004
- 30
Effects of diazepam and scopolamine on storage, retrieval and organizational processes in memory
- Psychology, Medicine
- Psychopharmacologia
- 2004
- 130
Effects of aging and dementia upon recent visuospatial memory
- Psychology, Medicine
- Neurobiology of Aging
- 1985
- 114
Short-term memory in the rhesus monkey: Disruption from the anti-cholinergic scopolamine
- Psychology, Medicine
- Pharmacology Biochemistry and Behavior
- 1976
- 319
Human memory and the cholinergic system. A relationship to aging?
- Psychology, Medicine
- Archives of neurology
- 1974
- 1,320
- Highly Influential
Aging in the rhesus monkey: debilitating effects on short-term memory.
- Medicine
- Journal of gerontology
- 1978
- 265
Implications of memory and language dysfunction in the naming deficit of senile dementia
- Psychology, Medicine
- Brain and Language
- 1987
- 128
A visual recognition memory test for the assessment of cognitive function in aging and dementia.
- Psychology, Medicine
- Experimental aging research
- 1987
- 43