Scopolamine as an Antidepressant: A Systematic Review
@article{Jaffe2013ScopolamineAA, title={Scopolamine as an Antidepressant: A Systematic Review}, author={Robert J. Jaffe and V. Novakovic and E. Peselow}, journal={Clinical Neuropharmacology}, year={2013}, volume={36}, pages={24–26} }
ObjectivesThe cholinergic-adrenergic hypothesis of mania and depression states that depression is characterized by an increase in central cholinergic activity relative to noradrenergic tone. Scopolamine is a centrally acting competitive inhibitor of the muscarinic cholinergic receptor site. This review seeks to find all available data investigating scopolamine as an antidepressant. MethodsA systematic review of all the published and unpublished or ongoing literature was conducted via Ovid… CONTINUE READING
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