Sclerostin antibody and interval treadmill training effects in a rodent model of glucocorticoid-induced osteopenia.

Abstract

Glucocorticoids have a beneficial anti-inflammatory and immunosuppressive effect, but their use is associated with decreased bone formation, bone mass and bone quality, resulting in an elevated fracture risk. Exercise and sclerostin antibody (Scl-Ab) administration have both been shown to increase bone formation and bone mass, therefore the ability of these… (More)
DOI: 10.1016/j.bone.2015.09.010

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