Scleroderma renal crisis: a rare but severe complication of systemic sclerosis.

  title={Scleroderma renal crisis: a rare but severe complication of systemic sclerosis.},
  author={Luc Mouthon and Alice B{\'e}r{\'e}zn{\'e} and Guillaume Bussone and L H No{\"e}l and P Villiger and Lo{\"i}c Guillevin},
  journal={Clinical reviews in allergy & immunology},
  volume={40 2},
Scleroderma renal crisis (SRC) is a major complication in patients with systemic sclerosis (SSc). It is characterized by malignant hypertension and oligo/anuric acute renal failure. SRC occurs in 5% of patients with SSc, particularly in the first years of disease evolution and in the diffuse form. The occurrence of SRC is more common in patients treated with glucocorticoids, the risk increasing with increasing dose. Left ventricular insufficiency and hypertensive encephalopathy are typical… CONTINUE READING
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