Scleroderma (progressive systemic sclerosis) inducing ureteral closure

At post-mortem examination of a 43-year-old male, scleroderma (progressive systemic sclerosis) localized to the kidneys and the right ureter was observed. The complete sclerodermatous obstruction of the ureter led to right-side hydronephrosis and chronic pyelonephritis. The sclerodermatous and pyelonephritic renal damage gave rise to malignant hypertension… (More)