Scientific validation of the antidiabetic effects of Syzygium jambolanum DC (black plum), a traditional medicinal plant of India.

@article{Baliga2013ScientificVO,
  title={Scientific validation of the antidiabetic effects of Syzygium jambolanum DC (black plum), a traditional medicinal plant of India.},
  author={Manjeshwar Shrinath Baliga and Saviona Fernandes and Karadka Ramdas Thilakchand and Prema D'souza and Srinath Rao},
  journal={Journal of alternative and complementary medicine},
  year={2013},
  volume={19 3},
  pages={
          191-7
        }
}
BACKGROUND In spite of the tremendous progress achieved in medical sciences in the last century, the management of diabetes mellitus, a disease as old as mankind, is poor. Diabetes is currently the world's largest endocrine disorder, and estimates are that it affects almost 5% of the population. Ayurveda, the Indian traditional system of medicine, is one of the world's oldest systems to have documented the diagnosis and treatment of diabetes. METHODS Experimental studies performed in… 
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References

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Hypoglycemic activity of inorganic constitutents in Eugenia jambolana seed on streptozotocin-induced diabetes in rats
TLDR
The conclusion that the inorganic constituents might play a important role in the antidiabetic nature E. jambolana seeds was reached.
Treatment with extracts of Eugenia jambolana seed and Aegle marmelos leaf prevents hyperglycemia and hyperlipidemia in alloxan induced diabetic rats.
TLDR
The histological studies of the endocrine region of pancreas of diabetic animals revealed that shrinkage of β cells of islets of langerhans was revealed and restoration of β-cells was evident at higher dose level that is, 400 mg/by wt extracts fed groups.
Anti-diabetic activity of Syzygium cumini and its isolated compound against streptozotocin-induced diabetic rats
TLDR
The results of this experimental study indicate that isolated compound ‘Mycaminose’, ethyl acetate and methanol extracts possess anti-diabetic effects against STZ-induced diabetic rats.
Chemical composition and in vitro antioxidant studies on Syzygium cumini fruit.
TLDR
Jamun pulp ethanol extract, kernel ethanol extract and seed coat ethanol extract showed a high degree of phenolic enrichment and inhibition of lipid peroxidation of the extracts was studied and their activity against peroxide radicals were lower than that of standard compounds.
Preclinical evaluation of the antidiabetic effect of Eugenia jambolana seed powder in streptozotocin-diabetic rats.
TLDR
Data on the antidiabetic effect of E. jambolana seed are adequate for approval of phase 2 clinical trials to evaluate this seed powder as complementary therapy in type 2 and type 1 diabetes.
Ameliorative Effect of Active Principle Isolated from Seeds of Eugenia jambolana on Carbohydrate Metabolism in Experimental Diabetes
TLDR
It is demonstrated that LH II possesses potent antidiabetic activity and it is effective in both MD and SD rabbits.
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