Scientific perspectives on drug transporters and their role in drug interactions.

@article{Zhang2006ScientificPO,
  title={Scientific perspectives on drug transporters and their role in drug interactions.},
  author={Lei Zhang and John M. Strong and Wei Qiu and Lawrence J. Lesko and S Huang},
  journal={Molecular pharmaceutics},
  year={2006},
  volume={3 1},
  pages={62-9}
}
Recently, increased interest in drug transporters and research in this area has revealed that drug transporters play an important role in modulating drug absorption, distribution, and elimination. Acting alone or in concert with drug metabolizing enzymes they can affect the pharmacokinetics and pharmacodynamics of a drug. This commentary will focus on the potential role that drug transporters may play in drug-drug interactions and what information may be needed during drug development and new… CONTINUE READING

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