Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments?

@inproceedings{Kell2012ScientificDA,
  title={Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments?},
  author={Douglas B. Kell},
  booktitle={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2012}
}
A considerable number of areas of bioscience, including gene and drug discovery, metabolic engineering for the biotechnological improvement of organisms, and the processes of natural and directed evolution, are best viewed in terms of a 'landscape' representing a large search space of possible solutions or experiments populated by a considerably smaller… CONTINUE READING