Scientific contributions of A. V. Hill: exercise physiology pioneer.
@article{Bassett2002ScientificCO, title={Scientific contributions of A. V. Hill: exercise physiology pioneer.}, author={David Bassett}, journal={Journal of applied physiology}, year={2002}, volume={93 5}, pages={ 1567-82 } }
Beginning in 1910, A. V. Hill performed careful experiments on the time course of heat production in isolated frog muscle. [] Key Method Hill and his colleagues made measurements of O(2) consumption on themselves and other subjects running around an 85-m grass track. In the process of this work, they defined the terms "maximum O(2) intake," "O(2) requirement," and "steady state of exercise." Other contributions of Hill include his discoveries of heat production in nerve, the series elastic component, and the…
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References
SHOWING 1-10 OF 137 REFERENCES
Maximal oxygen uptake: "old" and "new" arguments for a cardiovascular limitation.
- MedicineMedicine and science in sports and exercise
- 1992
The research performed over the last 100 yr in regard to oxygen transport during exercise is reviewed. Special focus is on major shifts in views held on which link may limit maximal oxygen uptake of…
The relation between the work performed and the energy liberated in muscular contraction
- EngineeringThe Journal of physiology
- 1924
The purpose of this paper is to discuss the significance of the term kW, particularly from the point of view of the theory that a stimulated muscle can be regarded as an elastic body, and to present further experiments which make possible a more detailed analysis of the excess energy, kW.
A quantitative comparison between the energy liberated and the work performed by the isolated sartorius muscle of the frog
- BiologyThe Journal of physiology
- 1923
It can now be shown that there is a fairly good quantitative relation between the heat production of muscles and the work which they perform, and that a muscle which does work liberates, ipsofacto, an extra supply of energy which does not appear in an isometric contraction.
A.V. Hill, C.H., F.R.S. - an appreciation.
- EducationBritish journal of sports medicine
- 1976
To present an appreciation of A. V. Hill is to follow in the wake of a long and impressive list of others who have honoured this quite remarkable man. Certainly there has been variety. The earliest I…
The Dynamics of Muscular Contraction
- Biology
- 1924
Part I is an account of experiments which prove that the same general type of relation between work and speed of shortening occurs in isolated muscle, and the phenomera investigated are not due primarily to an intervention of the nervous system, but to some fundamental character of the muscle fibre itself.
Total Energy Production and Phosphocreatine Hydrolysis in the Isotonic Twitch
- BiologyThe Journal of general physiology
- 1963
It is concluded that phosphocreatine hydrolysis and its associated buffer reactions can account quantitatively for the total energy output of isometric and isotonic twitches.
Muscular exercise, lactic acid, and the supply and utilisation of oxygen
- Chemistry, Biology
- 1925
Muscular Exercise, Lactic Acid, and the Supply and Utilisation of Oxygen
- Biology
- 1924
The method of studying the respiratory exchanges of man employed throughout our investigation has been that of the Douglas bag. No other method allows the same facility and accuracy in following a…
Muscular exercise, lactic acid and the supply and utilisation of oxygen.— Parts VII–VIII
- Environmental Science
- 1924
(A) The relation between oxygen intake and severity of exertion . — When muscular exercise commences, the ventilation of the lungs, the oxygen intake and the carbon dioxide output rise rapidly, in a…
The changes in respiration at the transition from work to rest
- EducationThe Journal of physiology
- 1920
The present paper proposes to deal with another transitional state, namely the transition from work to rest, using Krogh's bicycle ergometer and respiration apparatus, and draws b-samples of alveolar air corresponding to the former.