Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration.

@article{Barril1988SciaticNN,
  title={Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration.},
  author={Jos{\'e} Barril and Eugenio Vilanova and Mar{\'i}a de la Cruz Pell{\'i}n},
  journal={Toxicology},
  year={1988},
  volume={49 1},
  pages={107-14}
}
Some organophosphorus compounds (OP) induce a delayed polyneuropathy (OPIDP) which is initiated by the phosphorylation of the so-called neuropathy target esterase (NTE). In this work some aspects of hen sciatic nerve NTE are studied. The assay method is reported and modifications are discussed and a combined method proposed. Proximo-distal distribution showed a significant difference from proximal (100 +/- 10%) to distal (69 +/- 9%) fragments, in accordance with reported data. The time course… CONTINUE READING
1 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…