Sciatic Nerve Resection: Is That Truly an Indication for Amputation?

  title={Sciatic Nerve Resection: Is That Truly an Indication for Amputation?},
  author={Jacob Bickels and James C. Wittig and Yehuda Kollender and Kristen L. Kellar-Graney and Martin M Malawer and Isaac Meller},
  journal={Clinical Orthopaedics and Related Research},
En bloc resection of the sciatic nerve with an adjacent bone or soft tissue tumor has been assumed to be associated with a poor functional outcome and, therefore, was considered an indication for amputation. Although many surgical oncologists today challenge this assumption and do limb-sparing resection in these patients, a report of the functional outcome of a series of patients who had this procedure has not been published. Between 1991 and 1999, the authors treated 15 patients who had… 

Complete Femoral Nerve Resection with Soft Tissue Sarcoma: Functional Outcomes

Femoral nerve resection appears more morbid than anticipated and nerve-specific functional implications should be considered when counseling patients in preparation for possible resection of the femoral nerve when it is directly involved by a soft tissue sarcoma.

Two case reports of fair lower limb function after sciatic nerve sacrifice for the treatment of a malignant peripheral nerve sheath tumor

Surgical management of two cases of malignant peripheral nerve sheath tumor and a 10-year-old girl, requiring a limb salvage procedure with sacrifice of the sciatic nerve show fair functional outcomes.

Limb-Salvage Surgery of Soft Tissue Sarcoma with Sciatic Nerve Involvement

In a cohort of carefully selected patients with STS and sciatic nerve involvement, the extent of Sciatic nerve resection had no significant impact on disease recurrence or survival.

Epineural Dissection Is a Safe Technique That Facilitates Limb Salvage Surgery

It is concluded that epineural dissection (when combined with radiotherapy in a planned multidisciplinary approach to limb salvage) is both a safe and effective procedure to preserve the sciatic nerve and that nerve resection should be limited to situations where the nerve is completely encased in tumor.

Massive intercalary reconstruction of lower limb after wide excision of malignant tumors: an alternative to amputation or rotationplasty.

In this study, we present the feasibility of intercalary limb resection and massive reconstruction for malignant tumors of lower extremity. Ten cases of lower extremity malignancies that had

The management and outcome of large volume liposarcomas encasing the sciatic nerve.

Amputation for soft-tissue sarcoma.

Peripheral nerve considerations in the management of extremity soft tissue sarcomas.

For the situation in which postoperative function is already expected to be compromised due to vascular, bone, or extensive soft tissue resection, nerve resection may be the ultimate deciding factor in recommending amputation rather than limb salvage.

Popliteal Sarcomas: Presentation, Prognosis, and Limb Salvage

This study retrospectively analyzed the data of 29 consecutive patients operated on between 1989 and 2003 to ascertained the mode of initial presentation, the rates of local recurrence and distant metastasis, and the morbidity and complications of limb salvage procedures.

Sciatic and Femoral Nerve Resection During Extended Radical Surgery for Advanced Pelvic Tumours

En bloc sciatic and femoral nerve resection can be performed during extended radical pelvic resection with morbidity and survival outcomes comparable with existing exenteration literature, including in patients with recurrent rectal cancer.



A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system.

The need for a standardized system of end result reporting of various surgical alternatives after limb salvaging and ablative procedures for musculoskeletal tumors was clearly recognized during the

Soft tissue sarcoma involving the sciatic nerve

  • M. Brennan
  • Medicine
    The British journal of surgery
  • 2000
This issue addresses the problem of a sarcoma in the posterior aspect of the thigh where at operation the lesion is unexpectedly found to involve the sciatic nerve.

Isolated metastases to peripheral nerves. Report of five cases involving the brachial plexus

The brachial plexus is an uncommon site of blood‐born metastases of tumor invasion of the peripheral nervous system from different types of cancer and in various anatomic locations, and is considered a rare phenomenon.

Transtibial Amputation for Sciatic Nerve Loss; Saphenous Sensate Residual Limb

The authors have designed a long medial sensate myocutancous flap down to the foot based on the saphenous branch of the femoral nerve that resulted in good sensation over the entire transtibial residual limb.

Resection of the Posterior Compartment of the Thigh

This chapter discusses the anatomic considerations, staging studies, techniques of biopsy and indications and contraindications to the treatment of posterior thigh sarcomas.

Thigh: Surgical Features

  • In Enneking WF (ed). Musculoskeletal Tumor Surgery
  • 1983

Musculoskeletal Surgery for Cancer. Principles and Practice

  • Thieme Medical Pub
  • 1992