Schwann cells promote the capability of neural stem cells to differentiate into neurons and secret neurotrophic factors

@inproceedings{Yu2017SchwannCP,
  title={Schwann cells promote the capability of neural stem cells to differentiate into neurons and secret neurotrophic factors},
  author={Ziwei Yu and Yongzhi Men and Pin Dong},
  booktitle={Experimental and therapeutic medicine},
  year={2017}
}
The present study investigated whether co-culturing Schwann cells (SCs) with neural stem cells (NSCs) improves viability, direction of differentiation and secretion of brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) in NSCs. The three groups assessed were as follows: SCs, NSCs, and a co-culture of SCs and NSCs. Cellular morphological changes were observed under an inverted phase contrast microscope and quantified. Cells were identified by… CONTINUE READING

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