Schwann cell transplantation improves reticulospinal axon growth and forelimb strength after severe cervical spinal cord contusion.

@article{Schaal2007SchwannCT,
  title={Schwann cell transplantation improves reticulospinal axon growth and forelimb strength after severe cervical spinal cord contusion.},
  author={Sandra Marie Schaal and Brandon M Kitay and Kyung Suck Cho and Thomas Lo and David J. Barakat and A Marcillo and Andre R. Sanchez and Christian M. Andrade and Damien D Pearse},
  journal={Cell transplantation},
  year={2007},
  volume={16 3},
  pages={207-28}
}
Schwann cell (SC) implantation alone has been shown to promote the growth of propriospinal and sensory axons, but not long-tract descending axons, after thoracic spinal cord injury (SCI). In the current study, we examined if an axotomy close to the cell body of origin (so as to enhance the intrinsic growth response) could permit supraspinal axons to grow onto SC grafts. Adult female Fischer rats received a severe (C5) cervical contusion (1.1 mm displacement, 3 KDyn). At 1 week postinjury, 2… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…