Schwann cell multiplication in Trembler mice.

  title={Schwann cell multiplication in Trembler mice.},
  author={Charles S Perkins and Albert J. Aguayo and Garth M. Bray},
  journal={Neuropathology and applied neurobiology},
  volume={7 2},
Peripheral nerves of the mutant mouse Trembler are characterized by a severe myelin deficit and an increased number of Schwann cells. On the basis of radioautographic and quantitative morphologic investigations, the present study documents: i an abnormal persistence of post-natal Schwann cell proliferation in Trembler mouse nerves which, in unaffected animals, are composed of myelinated fibres; ii normal morphology, numbers and proliferation of Schwann cells in the unmyelinated (Remak) fibres… CONTINUE READING

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