Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases.

@article{Zhou2002SchizosaccharomycesPP,
  title={Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases.},
  author={Jin-Qiu Zhou and Haiyan Qi and Vincent P Schulz and Maria K. Mateyak and Ellen K Monson and Virginia A. Zakian},
  journal={Molecular biology of the cell},
  year={2002},
  volume={13 6},
  pages={
          2180-91
        }
}
The Saccharomyces cerevisiae Pif1p DNA helicase is the prototype member of a helicase subfamily conserved from yeast to humans. S. cerevisiae has two PIF1-like genes, PIF1 itself and RRM3, that have roles in maintenance of telomeric, ribosomal, and mitochondrial DNA. Here we describe the isolation and characterization of pfh1+, a Schizosaccharomyces pombe gene that encodes a Pif1-like protein. Pfh1p was the only S. pombe protein with high identity to Saccharomyces Pif1p. Unlike the two S… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 40 CITATIONS

To peep into Pif1 helicase: Multifaceted all the way from genome stability to repair-associated DNA synthesis

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

nwinding the functions of the Pif 1 family helicases

VIEW 12 EXCERPTS
CITES BACKGROUND & RESULTS

The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase.

VIEW 14 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

The functions of the multi-tasking Pfh1Pif1 helicase

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases

VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast.

VIEW 4 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 57 REFERENCES

DNA sequences at the telomeres of the fission yeast Schizosaccharomyces pombe

  • N. Sugawara
  • Ph.D. Thesis
  • 1989
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

The Pif1p helicase, a catalytic inhibitor of telomerase lengthening of yeast

  • Zhou, J.-Q, +4 authors V. A. Zakian
  • telomeres. Science
  • 2000
VIEW 15 EXCERPTS
HIGHLY INFLUENTIAL