Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae

@article{Lantermann2010SchizosaccharomycesPG,
  title={Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae},
  author={Alexandra B Lantermann and Tobias Straub and Annelie Str{\aa}lfors and Guocheng Yuan and Karl Ekwall and Philipp Korber},
  journal={Nature Structural &Molecular Biology},
  year={2010},
  volume={17},
  pages={251-257}
}
Positioned nucleosomes limit the access of proteins to DNA and implement regulatory features encoded in eukaryotic genomes. Here we have generated the first genome-wide nucleosome positioning map for Schizosaccharomyces pombe and annotated transcription start and termination sites genome wide. Using this resource, we found surprising differences from the previously published nucleosome organization of the distantly related yeast Saccharomyces cerevisiae. DNA sequence guides nucleosome… CONTINUE READING
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