Schizosaccharomyces pombe Mti2 and Mti3 act in conjunction during mitochondrial translation initiation

  title={Schizosaccharomyces pombe Mti2 and Mti3 act in conjunction during mitochondrial translation initiation},
  author={Ying Luo and R. Su and Yirong Wang and Wanqiu Xie and Zecheng Liu and Ying Huang},
  journal={The FEBS Journal},
Mitochondrial DNA encodes key subunits of the oxidative phosphorylation complexes essential for ATP production. Translation initiation in mitochondria requires two general factors, mtIF2 and mtIF3, whose counterparts in bacteria are essential for protein synthesis. In this study, we report the characterization of the fission yeast Schizosaccharomyces pombe mtIF2 (Mti2) and mtIF3 (Mti3). Deletion of mti2 impairs cell growth on the respiratory medium. The growth defect of the mti2 deletion mutant… Expand
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