Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21

@article{Blouin1998SchizophreniaSL,
  title={Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21},
  author={Jean Louis Blouin and Beth A. Dombroski and Swapan K Nath and Virginia K. Lasseter and Paula S. Wolyniec and Gerald Nestadt and Mary H. Thornquist and Gail Ullrich and John J. McGrath and Laura M Kasch and Malgorzata Lamacz and Marion Thomas and Corinne Gehrig and Uppala Radhakrishna and Sarah E. Snyder and Katherine G. Balk and Karin Jane Neufeld and Karen L. Swartz and Nicola DeMarchi and George N. Papadimitriou and Dimitris Dikeos and C. Stefanis and Aravinda Chakravarti and Barton Childs and David E Housman and Haig H. Kazazian and Stylianos E. Antonarakis and Ann E Pulver},
  journal={Nature Genetics},
  year={1998},
  volume={20},
  pages={70-73}
}
Schizophrenia is a common disorder characterized by psychotic symptoms; diagnostic criteria have been established. Family, twin and adoption studies suggest that both genetic and environmental factors influence susceptibility (heritability is approximately 71%; ref. 2), however, little is known about the aetiology of schizophrenia. Clinical and family studies suggest aetiological heterogeneity. Previously, we reported that regions on chromosomes 22, 3 and 8 may be associated with susceptibility… Expand
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Linkage of familial schizophrenia to chromosome 13q32.
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These results provide independent significant evidence of linkage of a schizophrenia-susceptibility locus to markers on 13q32 and support the presence of a second susceptibility locus on 8p21. Expand
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