Schizophrenia patients demonstrate a distinctive pattern of decision-making impairment on the Iowa Gambling Task.

@article{Shurman2005SchizophreniaPD,
  title={Schizophrenia patients demonstrate a distinctive pattern of decision-making impairment on the Iowa Gambling Task.},
  author={Brett D Shurman and William P. Horan and Keith H. Nuechterlein},
  journal={Schizophrenia research},
  year={2005},
  volume={72 2-3},
  pages={215-24}
}
Although dorsolateral prefrontal cortex (DLPFC) abnormalities in schizophrenia are well established, several lines of evidence suggest the orbitofrontal cortex (OFC) may also be dysfunctional in this disorder. We examined the performance of schizophrenia patients and nonpatient controls on the Iowa Gambling Task [Cognition 50 (1994) 7], a decision-making task sensitive to OFC damage that involves a series of selections from four decks of cards that vary in their reward/punishment profiles… CONTINUE READING
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