Schizophrenia hippocampus has elevated expression of chondrex glycoprotein gene.

@article{Chung2003SchizophreniaHH,
  title={Schizophrenia hippocampus has elevated expression of chondrex glycoprotein gene.},
  author={Carmen Chung and Teresa Tallerico and Philip Seeman},
  journal={Synapse},
  year={2003},
  volume={50 1},
  pages={
          29-34
        }
}
To identify genes associated with schizophrenia, DNA microarray chips were used to compare schizophrenia and control hippocampus tissues, revealing four genes with elevated expression, chondrex (or YKL-40), histamine-releasing factor, HERC2, and heat-shock 70. However, using the quantitative real-time polymerase chain reaction method, only the expression of the chondrex gene, an extracellular matrix glycoprotein involved in cell growth and migration, was found to be significantly elevated, by 1… CONTINUE READING

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