Schizophrenia as a progressive brain disease.

  title={Schizophrenia as a progressive brain disease.},
  author={Neeltje E.M . van Haren and Wiepke Cahn and Hilleke E. Hulshoff Pol and Ren{\'e} S. Kahn},
  journal={European psychiatry : the journal of the Association of European Psychiatrists},
  volume={23 4},
There is convincing evidence that schizophrenia is characterized by abnormalities in brain volume. At the Department of Psychiatry of the University Medical Centre Utrecht, Netherlands, we have been carrying out neuroimaging studies in schizophrenia since 1995. We focused our research on three main questions. First, are brain volume abnormalities static or progressive in nature? Secondly, can brain volume abnormalities in schizophrenia be explained (in part) by genetic influences? Finally, what… CONTINUE READING

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