Schizophrenia Gene Networks and Pathways and Their Applications for Novel Candidate Gene Selection

Abstract

BACKGROUND Schizophrenia (SZ) is a heritable, complex mental disorder. We have seen limited success in finding causal genes for schizophrenia from numerous conventional studies. Protein interaction network and pathway-based analysis may provide us an alternative and effective approach to investigating the molecular mechanisms of schizophrenia. METHODOLOGY… (More)
DOI: 10.1371/journal.pone.0011351

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