Schistosomes of small mammals from the Lake Victoria Basin, Kenya: new species, familiar species, and implications for schistosomiasis control

  title={Schistosomes of small mammals from the Lake Victoria Basin, Kenya: new species, familiar species, and implications for schistosomiasis control},
  author={Ben Hanelt and Ibrahim N Mwangi and Joseph M. Kinuthia and Geoffrey M. Maina and Lelo E. Agola and Martin W. Mutuku and Michelle L. Steinauer and Bernard R Agwanda and L Kigo and Ben N. Mungai and Eric S Loker and Gerald M. Mkoji},
  pages={1109 - 1118}
SUMMARY Recent schistosomiasis control efforts in sub-Saharan Africa have focused nearly exclusively on treatment of humans with praziquantel. However, the extent to which wild mammals act as reservoirs for Schistosoma mansoni and therefore as sources of renewed transmission following control efforts is poorly understood. With the objective to study the role of small mammals as reservoir hosts, 480 animals belonging to 9 rodent and 1 insectivore species were examined for infection with… 

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Rodents as Natural Hosts of Zoonotic Schistosoma Species and Hybrids: An Epidemiological and Evolutionary Perspective From West Africa

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The most likely hypothesis is that local people initially infected in 2013 re-contaminated the river during subsequent summers, however the possibility of an animal species acting as reservoir host remains, however it is unlikely that neither rats nor ruminants play a significant role in the maintenance of schistosomiasis outbreak in Corsica.

Antagonism between parasites within snail hosts impacts the transmission of human schistosomiasis

It is discovered the abundant cattle trematode, Calicophoron sukari, fails to develop in Biomphalaria pfeifferi unless S. mansoni larvae are present in the same snail, thereby limiting transmission of this human pathogen.

Out of Animals and Back Again: Schistosomiasis as a Zoonosis in Africa

An overview of zoonoses involving schistosomiasis is provided, focusing on Africa where the burden of the disease is highest, and the ways in which this information can be integrated into more effective conservation management and human disease control strategies are discussed.

Multihost Transmission of Schistosoma mansoni in Senegal, 2015–2018

The phylogenetic framework confirmed the presence of multiple S. mansoni lineages that could infect both humans and rodents; divergence times of these lineages varied and it was proposed that extensive movement of persons across West Africa might have contributed to the establishment of these various multihost S.mansoni clades.

Hybridizations within the Genus Schistosoma: implications for evolution, epidemiology and control

How early phenotypic identification and recent confirmation through molecular studies on naturally occurring infections, combined with experimental manipulations, have revealed evidence of viable hybridization and introgressions within and between human and animal schistosome species is reviewed.


This dissertation was to better understand transmission dynamics in a hyperendemic setting in western Kenya and to find alternative measures to supplement ongoing mass drug administration (MDA) using indigenous resources that disrupt the development of Schistosoma mansoni within its obligatory aquatic snail intermediate host, Biomphalaria.



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The data from this study indicate a lack of obvious spatial or temporal isolating mechanisms to prevent hybridization, raising the intriguing question of how the two species retain their separate identities.

Schistosoma kisumuensis n. sp. (Digenea: Schistosomatidae) from murid rodents in the Lake Victoria Basin, Kenya and its phylogenetic position within the S. haematobium species group

Comparison of approximately 3000-base-pair sequences of nuclear rDNA (partial 28S) and mtDNA ( partial cox1, nad6, 12S) strongly supports the status of Schistosoma kisumuensis as a new species and as a sister species of S. intercalatum.


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The results suggest that rodents participate in the transmission of intestinal schistosomiasis in Richard-Toll but the human population is the main source of infection.

An ecological field study of the water-rat Nectomys squamipes as a wild reservoir indicator of Schistosoma mansoni transmission in an endemic area.

The rodent infection rates of S. mansoni increased when rodent population sizes were lower, andCoprology and serology results presented the same trends along time and were correlated.

Animal reservoirs of schistosomiasis

It was Leiper who finally demonstrated the existence of S. haematobium and S. mansoni as two distinct species which had morphologically different adult worms and eggs, different distributions in the definitive hosts and a dependence on snails from different genera as intermediate hosts.

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N. squamipes has become a natural host of S. mansoni and possibly may participate in keeping the cycle of schistosomiasis transmission at Pamparrão Valley, and probably the same is likely to occur in natural conditions.

Introgressive hybridization of human and rodent schistosome parasites in western Kenya

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[Natural infection of wild rodents by Schistosoma mansoni].

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