Schistosomes: challenges in compound screening.

  title={Schistosomes: challenges in compound screening.},
  author={Bernadette Ramirez and Quentin Bickle and Fouad Yousif and Foluke Fakorede and Marie-Annick Mouri{\`e}s and Solomon Nwaka},
  journal={Expert opinion on drug discovery},
  volume={2 s1},
Major progress in studying the biology of schistosomes had been achieved since the late 1960s with the successful laboratory cultivation of the parasite's life cycle stages in the vertebrate (in vivo animal models) and snail hosts. This was followed by establishment of in vitro culture techniques for cultivation of the different life cycle stages to understand the mechanisms regulating the parasite's growth, development, transformation, pathogenicity and survival, with prospects to develop and… CONTINUE READING

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