Schistosoma mansoni population structure and persistence after praziquantel treatment in two villages of Bahia, Brazil.

@article{Blanton2011SchistosomaMP,
  title={Schistosoma mansoni population structure and persistence after praziquantel treatment in two villages of Bahia, Brazil.},
  author={Ronald E Blanton and Walter A. Blank and Jackson Maur{\'i}cio Lopes Costa and Theomira M A Carmo and Eliana Almeida Gomes Reis and Luciano Kalabric Silva and L Marilac Meireles Barbosa and Matthew R Test and Mitermayer G Reis},
  journal={International journal for parasitology},
  year={2011},
  volume={41 10},
  pages={1093-9}
}
Praziquantel has been used to treat schistosome infections since 1979 and currently is the only chemotherapeutic agent in production for this purpose, raising concerns about the potential for the emergence of drug resistance. In practice, 10-20% of infected patients will continue to excrete eggs after treatment. It is not understood to what degree this represents selection of a resistant population or incomplete elimination due to the presence of immature worms at the time of treatment. We used… CONTINUE READING
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