Schistosoma mansoni: the effect of dexamethasone on the cercaria-schistosomulum transformation, in vivo.

@article{Melo1994SchistosomaMT,
  title={Schistosoma mansoni: the effect of dexamethasone on the cercaria-schistosomulum transformation, in vivo.},
  author={A. L. de Melo and M. Hermeto and R. S. Bicalho and A. P. Vargas and F. Favaretto and L. H. Pereira},
  journal={Revista do Instituto de Medicina Tropical de Sao Paulo},
  year={1994},
  volume={36 1},
  pages={
          89-93
        }
}
Treatment with dexamethasone (DMS) in the early phases of the experimental Schistosoma mansoni infection causes an indirect effect on the cercaria-schistosomulum transformation process. This is observed when naive albino mice are treated with that drug (50 mg/Kg, subcutaneously) and infected intraperitoneally 01 hour later with about 500 S. mansoni cercariae (LE strain). An inhibition in the host cell adhesion to the larvae, with a simultaneous delay in the cercaria-schistosomulum… Expand
2 Citations
Exploring possibilities for an alternative approach in experimental schistosomiasis mansoni: the peritoneal cavity of mice
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The constitution and evolution of these cellular reactions at histology were similar to that of hepatic granuloma, and peritoneal granulomata were subject to the host immunomodulation. Expand
Phenotypic plasticity of male Schistosoma mansoni from the peritoneal cavity and hepatic portal system of laboratory mice and hamsters
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The present results reinforce the idea that S. mansoni has high plastic potential and adaptive capacity and significant morphometric alterations were observed when worms recovered from the portal system of both strains of mice were compared with the schistosomes obtained from hamsters. Expand

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