Schistosoma mansoni: cercaricidal effect of 2-tetradecenoic acid, a penetration stimulant.

@article{Haas1984SchistosomaMC,
  title={Schistosoma mansoni: cercaricidal effect of 2-tetradecenoic acid, a penetration stimulant.},
  author={Wilfried Haas},
  journal={Experimental parasitology},
  year={1984},
  volume={58 2},
  pages={
          215-22
        }
}
Schistosoma mansoni cercariae are stimulated by 2-tetradecenoic acid (TDA) to penetrate agar substrates. TDA simultaneously causes tegumental transformation similar to that seen when cercariae transform to schistosomula, reduces the Cercarienhüllen reaction in immune human serum, and reduces larval tolerance to water. TDA damages cercariae that fail to penetrate or have no opportunity to do so. This damage apparently stems from increased tegumental permeability to water. Preincubation in TDA… CONTINUE READING