Schemes of metabolic patterns of anabolic androgenic steroids for the estimation of metabolites of designer steroids in human urine
@article{Fragkaki2009SchemesOM, title={Schemes of metabolic patterns of anabolic androgenic steroids for the estimation of metabolites of designer steroids in human urine}, author={A. Fragkaki and Y. S. Angelis and A. Tsantili-Kakoulidou and M. Koupparis and C. Georgakopoulos}, journal={The Journal of Steroid Biochemistry and Molecular Biology}, year={2009}, volume={115}, pages={44-61} }
Unified metabolism schemes of anabolic androgenic steroids (AAS) in human urine based on structure classification of parent molecules are presented in this paper. Principal components analysis (PCA) was applied to AAS molecules referred in the World Anti-Doping Agency (WADA) list of prohibited substances, resulting to their classification into six distinct groups related to structure features where metabolic alterations usually occur. The metabolites of the steroids participating to these six… CONTINUE READING
Figures, Tables, and Topics from this paper
44 Citations
In Vitro Synthesis of Metabolites of three Anabolic Androgenic Steroids, by Human Liver Microsomes
- Chemistry
- 2013
ANALYTICAL METHODS FOR THE DETECTION OF NON- LABELED ANABOLIC ANDROGENIC STEROIDS IN FOOD SUPPLEMENTS
- Chemistry
- 2015
- 1
Urinary detection of conjugated and unconjugated anabolic steroids by dilute-and-shoot liquid chromatography-high resolution mass spectrometry.
- Chemistry, Medicine
- Drug testing and analysis
- 2015
- 27
Detection of designer steroid methylstenbolone in “nutritional supplement” using gas chromatography and tandem mass spectrometry: Elucidation of its urinary metabolites
- Chemistry, Medicine
- Steroids
- 2013
- 31
Current status and bioanalytical challenges in the detection of unknown anabolic androgenic steroids in doping control analysis.
- Chemistry, Medicine
- Bioanalysis
- 2013
- 14
Metabolism of methylstenbolone studied with human liver microsomes and the uPA⁺/⁺-SCID chimeric mouse model.
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 2014
- 14
Advances in the detection of designer steroids in anti-doping.
- Computer Science, Medicine
- Bioanalysis
- 2014
- 20
Drug-drug interaction and doping: Effect of non-prohibited drugs on the urinary excretion profile of methandienone.
- Chemistry, Medicine
- Drug testing and analysis
- 2018
- 3
References
SHOWING 1-10 OF 45 REFERENCES
Metabolism of anabolic steroids in man: synthesis and use of reference substances for identification of anabolic steroid metabolites
- Chemistry
- 1993
- 259
- Highly Influential
Metabolism of 4-hydroxyandrostenedione and 4-hydroxytestosterone: Mass spectrometric identification of urinary metabolites
- Chemistry, Medicine
- Steroids
- 2007
- 33
Studies on anabolic steroids—4. Identification of new urinary metabolites of methenolone acetate (primobolan®) in human by gas chromatography/mass spectrometry
- Chemistry, Medicine
- The Journal of Steroid Biochemistry and Molecular Biology
- 1990
- 28
Metabolism and excretion of anabolic steroids in doping control—New steroids and new insights
- Chemistry, Medicine
- The Journal of Steroid Biochemistry and Molecular Biology
- 2006
- 92
- Highly Influential
Studies on anabolic steroids. III. Detection and characterization of stanozolol urinary metabolites in humans by gas chromatography-mass spectrometry.
- Chemistry, Medicine
- Journal of chromatography
- 1989
- 61
- PDF
Gas chromatography/mass spectrometry characterization of urinary metabolites of danazol after oral administration in human.
- Medicine, Chemistry
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2006
- 8
Discovery, biosynthesis, and structure elucidation of metabolites of a doping agent and a direct analogue, tetrahydrogestrinone and gestrinone, using human hepatocytes.
- Chemistry, Medicine
- Analytical chemistry
- 2005
- 37
- PDF
Studies on anabolic steroids. II--Gas chromatographic/mass spectrometric characterization of oxandrolone urinary metabolites in man.
- Chemistry, Medicine
- Biomedical & environmental mass spectrometry
- 1989
- 33