Schema representation in patients with ventromedial PFC lesions.

  title={Schema representation in patients with ventromedial PFC lesions.},
  author={Vanessa E Ghosh and Morris Moscovitch and Brenda Melo Colella and Asaf Gilboa},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={34 36},
Human neuroimaging and animal studies have recently implicated the ventromedial prefrontal cortex (vmPFC) in memory schema, particularly in facilitating new encoding by existing schemas. In humans, the most conspicuous memory disorder following vmPFC damage is confabulation; strategic retrieval models suggest that aberrant schema activation or reinstatement plays a role in confabulation. This raises the possibility that beyond its role in schema-supported memory encoding, the vmPFC is also… CONTINUE READING
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