Scheduling of gemcitabine and cisplatin in Lewis lung tumour bearing mice.

Abstract

We used the gemcitabine (dFdC) and cisplatin (cis-diamine dichloroplatinum CDDP) resistant murine NSCLC tumour Lewis Lung (LL) in C57/B16 mice to optimise scheduling of both drugs, since in previous in vivo studies no effective combination schedule of both compounds was found to overcome resistance to either drug. dFdC could not be combined at the… (More)

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@article{Moorsel1999SchedulingOG, title={Scheduling of gemcitabine and cisplatin in Lewis lung tumour bearing mice.}, author={Catharina J A Van Moorsel and H M. Pinedo and Gijsbert Veerman and Jan Baptist Vermorken and Pieter E. Postmus and G. J. Peters}, journal={European journal of cancer}, year={1999}, volume={35 5}, pages={808-14} }