Scents and sense: In silico perspectives on olfactory receptors

  title={Scents and sense: In silico perspectives on olfactory receptors},
  author={Charleen G. Don and Sereina Riniker},
  journal={Journal of computational chemistry},
  volume={35 32},
Olfactory receptors (ORs) represent the largest subfamily of the superfamily G protein-coupled receptors (GPCRs). This family of membrane receptors functions as essential gateway for activation of many cellular signaling pathways. Finding universal principles underlying GPCR activation by studying ORs is important for the design of new therapeutics that target olfaction-related and other GPCR-malfunctioning diseases. In addition, gaining knowledge regarding the interactions between ORs and… CONTINUE READING


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M. Christen, P. H. Hnenberger, +11 authors J. Comput
2005, 26, • 1719

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