Scavenger receptors in innate immunity.

  title={Scavenger receptors in innate immunity.},
  author={Leanne Peiser and Subhankar Mukhopadhyay and Siamon Gordon},
  journal={Current opinion in immunology},
  volume={14 1},
Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells. They bind and internalise micro-organisms and their products including Gram-positive bacteria (lipoteichoic acid), Gram-negative bacteria (lipopolysaccharide), intracellular bacteria and CpG DNA. SR can alter cell morphology and their expression is… CONTINUE READING

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