Scavenger receptor BI transfers major lipoprotein-associated phospholipids into the cells.

@article{Urban2000ScavengerRB,
  title={Scavenger receptor BI transfers major lipoprotein-associated phospholipids into the cells.},
  author={Sinisa Urban and S Zieseniss and Moritz Werder and Helmut Hauser and R Budzinski and Bernd Engelmann},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 43},
  pages={33409-15}
}
The phospholipids of lipoproteins can be transferred to cells by an endocytosis-independent uptake pathway. We analyzed the role of scavenger receptor BI (SR-BI) for the selective cellular phospholipid import. Human monocytes rapidly acquired the pyrene (py)-labeled phospholipids sphingomyelin (SM), phosphatidylcholine, and phosphatidylethanolamine from different donors (low and high density lipoproteins (LDL, HDL), lipid vesicles). The anti-SR-BI antibody directed against the extracellular… CONTINUE READING

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