Scavenger receptor-BI is a receptor for lipoprotein(a).

  title={Scavenger receptor-BI is a receptor for lipoprotein(a).},
  author={X I A Yang and Marcelo J Amar and Boris L Vaisman and Alexander V Bocharov and Tatyana G. Vishnyakova and Lita A. Freeman and Roger J. Kurlander and Amy P. Patterson and Lewis C. Becker and Alan T Remaley},
  journal={Journal of lipid research},
  volume={54 9},
Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ligand. Stable cell lines (HEK293 and HeLa) expressing human SR-BI were incubated with protein- or lipid-labeled Lp(a) to investigate SR-BI-dependent Lp(a) cell association. SR-BI expression enhanced the association of both (125)I- and Alexa Fluor… CONTINUE READING


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