Scatter factor receptor (c-Met) as possible prognostic factor in patients with oral squamous cell carcinoma.

@article{Muzio2004ScatterFR,
  title={Scatter factor receptor (c-Met) as possible prognostic factor in patients with oral squamous cell carcinoma.},
  author={Lorenzo Lo Muzio and Rosalia Leonardi and Michele Davido Mignogna and Giuseppe Pannone and Corrado Rubini and Tiziana Pieramici and Lorenzo Trevisiol and Francesca Ferrari and Rosario Serpico and Nunzio Francesco Testa and Gaetano de Rosa and Stefania Staibano},
  journal={Anticancer research},
  year={2004},
  volume={24 2C},
  pages={1063-9}
}
This report was performed to study the biological role of c-Met in oral tumorigenesis by analyzing its expression in relation to clinicopathological features. Seventy-three cases of oral squamous cell carcinoma and 10 of normal mucosa were analysed for c-Met expression by immunohistochemistry. Normal oral squamous epithelium showed absent or low membranous positivity in the intermediate (malpighian-spinous) layer. Fifty-seven cases (78%) of carcinoma showed immunopositivity, with a prevalently… CONTINUE READING